<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2021 Workiva-->
<!--r:95ac6e47-48ee-4702-9068-b4e05f83aec6,g:d1ec82c4-42a3-48b4-a9dc-c2ecc0311d0b-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.viatris.com/role/CoverPage" xlink:type="simple" xlink:href="vtrs-20211108.xsd#CoverPage"/>
  <link:presentationLink xlink:role="http://www.viatris.com/role/CoverPage" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_c417574f-5ac1-4660-9e09-e91225bc0e57" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_DocumentType_c417574f-5ac1-4660-9e09-e91225bc0e57" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_54ed1221-3e45-41e2-a606-34f7af58820e" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_DocumentPeriodEndDate_54ed1221-3e45-41e2-a606-34f7af58820e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_4c2f7938-89f7-4ea9-acb2-e19941ed9f22" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_EntityRegistrantName_4c2f7938-89f7-4ea9-acb2-e19941ed9f22" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_ee927f26-2909-4a9c-8340-84f4808a89fb" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_EntityIncorporationStateCountryCode_ee927f26-2909-4a9c-8340-84f4808a89fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_dce66eeb-e21a-4ef6-9c67-48ddddd4fd89" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_EntityFileNumber_dce66eeb-e21a-4ef6-9c67-48ddddd4fd89" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_c9a53673-8c7d-43ad-8e4b-62973a903277" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_EntityTaxIdentificationNumber_c9a53673-8c7d-43ad-8e4b-62973a903277" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_7d70ce92-f6e5-4894-819b-34e9be0e684a" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_EntityAddressAddressLine1_7d70ce92-f6e5-4894-819b-34e9be0e684a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_39cf8a78-c61b-40d5-9645-cc72fc782eef" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_EntityAddressCityOrTown_39cf8a78-c61b-40d5-9645-cc72fc782eef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_6058eb65-6f8f-4b96-8e2f-bf24f1c0ce1b" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_EntityAddressPostalZipCode_6058eb65-6f8f-4b96-8e2f-bf24f1c0ce1b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_a48fcd4e-d759-4e5d-a12c-f6ed281f434c" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_CityAreaCode_a48fcd4e-d759-4e5d-a12c-f6ed281f434c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_9c4c4ca1-16b3-488c-a2c7-35cf1554562c" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_LocalPhoneNumber_9c4c4ca1-16b3-488c-a2c7-35cf1554562c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_e59b23f1-4c5f-4a0c-a2c0-da28e6bea360" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_WrittenCommunications_e59b23f1-4c5f-4a0c-a2c0-da28e6bea360" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_8d0482e6-3f26-4640-ac1d-9f64f4a55ec4" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_SolicitingMaterial_8d0482e6-3f26-4640-ac1d-9f64f4a55ec4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_34c2b7fe-0d54-4668-a5ca-79d872c9a6d0" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_PreCommencementTenderOffer_34c2b7fe-0d54-4668-a5ca-79d872c9a6d0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_305b6943-ad8b-477d-85cc-14ceb2b269c0" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_305b6943-ad8b-477d-85cc-14ceb2b269c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_db22e0e9-4e76-40a0-b512-5f8edad9b28e" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_TradingSymbol_db22e0e9-4e76-40a0-b512-5f8edad9b28e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_6fa94ecc-d412-4407-a76b-afe979715dcb" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_Security12bTitle_6fa94ecc-d412-4407-a76b-afe979715dcb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_e40ccd24-7b49-408f-bd0f-0d3b465f461c" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_SecurityExchangeName_e40ccd24-7b49-408f-bd0f-0d3b465f461c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_c86323a4-379f-421a-8e3f-a6a97a573b4e" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_EntityEmergingGrowthCompany_c86323a4-379f-421a-8e3f-a6a97a573b4e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_7df4a240-bf40-41aa-9fa7-a14c0d418709" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_AmendmentFlag_7df4a240-bf40-41aa-9fa7-a14c0d418709" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_6d08b19d-bddc-4119-a0eb-8ff40a936337" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_EntityCentralIndexKey_6d08b19d-bddc-4119-a0eb-8ff40a936337" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_6b60a448-5870-4cf1-b536-f0ecd52b9d86" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CityAreaCode"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_e97b0109-c799-4b1a-8675-96bd53b1c4f9" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_LocalPhoneNumber"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_5f5fdea0-6a1c-4bfd-89be-12bcab8fdcd9" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f3684f05-85de-49b3-b46d-db99b391417a" xlink:to="loc_dei_EntityAddressStateOrProvince_5f5fdea0-6a1c-4bfd-89be-12bcab8fdcd9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
