November 21, 2019

Michael Goettler
President
Upjohn Inc.
235 East 42nd Street
New York, NY 10017

       Re: Upjohn Inc.
           Registration Statement on Form 10
           Filed October 25, 2019
           File No. 000-56114

Dear Mr. Goettler:

       We have reviewed your filing and have the following comments. In some of
our
comments, we may ask you to provide us with information so we may better
understand your
disclosure.

       Please respond to these comments within ten business days by providing
the requested
information or advise us as soon as possible when you will respond. If you do
not believe our
comments apply to your facts and circumstances, please tell us why in your
response.

       After reviewing your response to these comments, we may have additional
comments.

Registration Statement on Form 10

General

1.    Pursuant to Section 12(g)(1) of the Exchange Act, the Form 10 becomes
effective
      automatically 60 days after the initial filing date. At that time, you
will be subject to the
      reporting requirements of the Exchange Act. In addition, we will continue
to review your
      filing until all of our comments have been addressed. If the review
process has not been
      completed before the effectiveness date you should consider withdrawing
the Form 10
      registration statement to prevent it from becoming effective and, as
applicable, file a new
      Form 10 registration at such time as you are able to respond to any
remaining issues or
      comments.
2.    Please amend the Form 10 registration statement, as applicable, to
address any relevant
      comments issued to you concerning your Form S-4 filed on October 25,
2019.
 Michael Goettler
FirstName LastNameMichael Goettler
Upjohn Inc.
Comapany 21, 2019
November NameUpjohn Inc.
Page 2
November 21, 2019 Page 2
FirstName LastName
        We remind you that the company and its management are responsible for
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments, action
or absence of
action by the staff.

       You may contact Franklin Wyman at 202-551-3660 or Kevin W. Vaughn,
Accounting
Branch Chief, at 202-551-3494 if you have questions regarding comments on the
financial
statements and related matters. Please contact Joseph McCann at 202-551-6262 or
Celeste
Murphy, Legal Branch Chief, at 202-551-3257 with any other questions.



                                                          Sincerely,

                                                          Division of
Corporation Finance
                                                          Office of Life
Sciences
cc:      David K. Lam